{"id":7350,"date":"2026-06-20T02:16:12","date_gmt":"2026-06-20T02:16:12","guid":{"rendered":"https:\/\/gothi.gov.eg\/?page_id=7350"},"modified":"2026-06-20T02:22:31","modified_gmt":"2026-06-20T02:22:31","slug":"%d8%aa%d9%82%d9%86%d9%8a%d8%a7%d8%aa-%d8%a7%d9%84%d8%a5%d8%ae%d8%b5%d8%a7%d8%a8-%d8%a7%d9%84%d9%85%d8%b3%d8%a7%d8%b9%d8%af","status":"publish","type":"page","link":"https:\/\/gothi.gov.eg\/?page_id=7350","title":{"rendered":"\u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0625\u062e\u0635\u0627\u0628 \u0627\u0644\u0645\u0633\u0627\u0639\u062f"},"content":{"rendered":"\t\t
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\n\n \n\n \n <\/path><\/svg> <\/span>\n\n \n <\/path><\/svg> <\/span>\n \n <\/span>\n \n \n Artificial Oocyte Activation (AOA) Following Intracytoplasmic Sperm Injection (ICSI) <\/span>\n\n <\/h5>\n\n
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\u00a0 \u00a0\u00a0Download Guideline<\/strong><\/u><\/a><\/strong><\/span><\/h4>

– Executive Summary<\/h3>

\u25aa\ufe0f\u00a0 IVF facilities could consider offering AOA for patients with previous no or low fertilisation, defined as lower than 30% (conditional recommendation).<\/p>

\u25aa\ufe0f\u00a0\u00a0AOA could be considered after proper counselling and well-informing the patients of globozoospermia cases (conditional recommendation).<\/p>

\u25aa\ufe0f\u00a0\u00a0IVF facilities should NOT recommend AOA for the general ICSI population (conditional recommendation against).<\/p>

\u25aa\ufe0f\u00a0\u00a0IVF facilities should NOT recommend AOA for improving embryo quality (conditional recommendation against).<\/p>

\u25aa\ufe0f\u00a0IVF facilities should NOT recommend AOA for improving embryo development and blastocyst formation (conditional recommendation against).<\/p>

\u25aa\ufe0f\u00a0\u00a0IVF facilities should NOT recommend rescue AOA either hours or on day 1 after ICSI (conditional recommendation against).<\/p>

\u25aa\ufe0f\u00a0\u00a0IVF facilities could consider sibling-oocyte-split if AOA is offered for patients of previous low or no fertilisation, given the scarce long-term safety data (good practice statment).<\/p>

\u25aa\ufe0f\u00a0\u00a0Except for globozoospermia cases, IVF facilities should NOT recommend AOA for ICSI cycle with male factor infertility and no history of no or low fertilisation (conditional recommendation against).<\/p>

\u25aa\ufe0f\u00a0\u00a0Except for the above recommendations, AOA should only be considered within a research context without charging the patients and after proper counselling and written consent (good practice statment).<\/p><\/div> <\/div>\n\n <\/div>\n

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\n\n \n\n \n <\/path><\/svg> <\/span>\n\n \n <\/path><\/svg> <\/span>\n \n <\/span>\n \n \n The Embryos to Transfer in IVF\/ICSI <\/span>\n\n <\/h5>\n\n
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